Annotation Detail

Information
Associated Genes
ACE
Associated Variants
rs1800764
rs1800764
Associated Disease
Impaired cognition
Source Database
DisGeNET
Description
At the level of genotypic association, we confirmed that the APOE ε4 homozygote significantly accelerated cognitive decline and found that carriers of the ACE rs1800764_C allele were more likely to show cognitive decline than noncarriers, particularly in those without college education.
Pubmed
24863667
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0077199245500874
Year of publication
2014
Drugs