Annotation Detail

Information
Associated Genes
TNFRSF1A
Associated Variants
TNFRSF1A c.625+10A>G ( ENST00000162749.7, ENST00000540022.5, ENST00000440083.7 )
TNFRSF1A c.625+10A>G ( ENST00000162749.7, ENST00000440083.7, ENST00000540022.5 )
Associated Disease
multiple sclerosis
Source Database
DisGeNET
Description
The TNF-α inverse association with relapse was only present among persons carrying the wild-type of the functional SNP rs1800693 in TNFRSF1A that has been previously associated with MS risk.
Pubmed
24790215
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.258816703696977
Year of publication
2015
Drugs