Annotation Detail

Information
Associated Genes
TNFRSF1A
Associated Variants
TNFRSF1A c.625+10A>G ( ENST00000162749.7, ENST00000540022.5, ENST00000440083.7 )
TNFRSF1A p.Arg121Pro (p.R121P) ( ENST00000440083.7, ENST00000540022.5, ENST00000162749.7 )
TNFRSF1A p.Arg121Gln (p.R121Q) ( ENST00000440083.7, ENST00000540022.5, ENST00000162749.7 )
TNFRSF1A c.625+10A>G ( ENST00000162749.7, ENST00000440083.7, ENST00000540022.5 )
TNFRSF1A p.Arg121Pro (p.R121P) ( ENST00000162749.7, ENST00000440083.7, ENST00000540022.5 )
TNFRSF1A p.Arg121Gln (p.R121Q) ( ENST00000162749.7, ENST00000440083.7, ENST00000540022.5 )
Associated Disease
multiple sclerosis
Source Database
DisGeNET
Description
[Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.]
Pubmed
19525953
Original source reporting the Gene Disease association
GAD
DisGENET score for the Gene Disease association
0.258816703696977
Year of publication
2009
Drugs