Annotation Detail

Information
Associated Genes
UCP1
Associated Variants
NC_000004.12:g.140572807T>C
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
NC_000004.12:g.140572807T>C
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
Associated Disease
Metabolic syndrome X
Source Database
DisGeNET
Description
We investigated whether the -3826A/G polymorphism (rs1800592) of the uncoupling protein 1 gene (UCP1) and the Trp64Arg polymorphism (rs4994) of the β3-adrenergic receptor gene (ADRB3) are associated with type 2 diabetes mellitus (T2DM) and features of metabolic syndrome in a Brazilian-Caucasian population.
Pubmed
24138564
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00399568321108385
Year of publication
2014
Drugs