Annotation Detail

Information
Associated Genes
TTR
Associated Variants
TTR MUTATION
TTR MUTATION
Associated Disease
Adenomatous Polyposis Coli
Source Database
DisGeNET
Description
Our research suggests that impairment of autophagy might be involved in the pathogenesis of TTR FAP with Y114C mutation, and curcumin might be a potential therapeutic approach for TTR FAP.
Pubmed
25382970
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0298586059288334
Drugs