Annotation Detail

Information
Associated Genes
TNNC1
Associated Variants
TNNC1 p.Gly159Asp (p.G159D) ( ENST00000232975.8 )
TNNC1 p.Leu29Gln (p.L29Q) ( ENST00000232975.8 )
TNNC1 p.Gly159Asp (p.G159D) ( ENST00000232975.8 )
TNNC1 p.Leu29Gln (p.L29Q) ( ENST00000232975.8 )
Associated Disease
Cardiomyopathies
Source Database
DisGeNET
Description
Challenging current paradigms related to cardiomyopathies. Are changes in the Ca2+ sensitivity of myofilaments containing cardiac troponin C mutations (G159D and L29Q) good predictors of the phenotypic outcomes?
Pubmed
18820258
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0048958852191096
Year of publication
2008
Drugs