Annotation Detail

Information
Associated Genes
TNNC1
Associated Variants
TNNC1 p.Gly159Asp (p.G159D) ( ENST00000232975.8 )
TNNC1 p.Leu29Gln (p.L29Q) ( ENST00000232975.8 )
TNNC1 p.Gly159Asp (p.G159D) ( ENST00000232975.8 )
TNNC1 p.Leu29Gln (p.L29Q) ( ENST00000232975.8 )
Associated Disease
hypertrophic cardiomyopathy
Source Database
DisGeNET
Description
Two novel mutations (G159D and L29Q) in cardiac troponin C (CTnC) associate their phenotypic outcomes with dilated (DCM) and hypertrophic cardiomyopathy (HCM), respectively.
Pubmed
18820258
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00990139104839396
Year of publication
2008
Drugs