Annotation Detail

Information
Associated Genes
CTLA4
Associated Variants
CTLA4 MUTATION
CTLA4 MUTATION
Associated Disease
pneumonia
Source Database
DisGeNET
Description
Here we showed that a lack of ICOS on murine ILC2s and blocking the ICOS:ICOS-ligand interaction in human ILC2s reduced AHR and lung inflammation.
Pubmed
25769613
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs