Annotation Detail

Information
Associated Genes
DRD2
Associated Variants
ANKK1 p.Glu713Lys (p.E713K) ( ENST00000303941.4 )
DRD2 p.Pro319= (p.P319=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
ANKK1 p.Glu713Lys (p.E713K) ( ENST00000303941.4 )
DRD2 p.Pro319= (p.P319=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
Associated Disease
INTELLIGENCE QUANTITATIVE TRAIT LOCUS 1
Source Database
DisGeNET
Description
The DRD2 C:C genotype of rs6277 was associated with decreased general cognitive ability 'g' (p = 0.003), and DRD2 rs1800497 heterozygotes had lowest mean general cognitive ability 'g' (p = 0.007).
Pubmed
20567893
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2010
Drugs