Annotation Detail

Information
Associated Genes
DRD2
Associated Variants
ANKK1 p.Glu713Lys (p.E713K) ( ENST00000303941.4 )
DRD2 c.*52G>A ( ENST00000542968.5, ENST00000538967.5, ENST00000362072.8, ENST00000346454.7, ENST00000544518.5 )
DRD2 p.Pro319= (p.P319=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
ANKK1 p.Glu713Lys (p.E713K) ( ENST00000303941.4 )
DRD2 c.*52G>A ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
DRD2 p.Pro319= (p.P319=) ( ENST00000346454.7, ENST00000362072.8, ENST00000538967.5, ENST00000542968.5, ENST00000544518.5 )
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
Some common single-nucleotide polymorphisms (SNPs; rs6276, rs6277, and rs1800497) in the human DRD2 gene are associated with decreased D2R expression and function, as well as high blood pressure.
Pubmed
24379187
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.121628651232482
Year of publication
2014
Drugs