Annotation Detail
Information
- Associated Genes
- DRD2
- Associated Variants
-
ANKK1 p.Glu713Lys (p.E713K)
(
ENST00000303941.4 )
DRD2 c.*725G>T ( ENST00000544518.5, ENST00000542968.5, ENST00000362072.8, ENST00000346454.7 )
DRD2 c.-31-17985A>G ( ENST00000362072.8, ENST00000346454.7 )
DRD2 c.-31-24048C>T ( ENST00000346454.7, ENST00000362072.8 )
DRD2 c.-32+16024T>G ( ENST00000362072.8, ENST00000346454.7 )
ANKK1 p.Glu713Lys (p.E713K) ( ENST00000303941.4 )
DRD2 c.*725G>T ( ENST00000346454.7, ENST00000362072.8, ENST00000542968.5, ENST00000544518.5 )
DRD2 c.-31-17985A>G ( ENST00000346454.7, ENST00000362072.8 )
DRD2 c.-31-24048C>T ( ENST00000346454.7, ENST00000362072.8 )
DRD2 c.-32+16024T>G ( ENST00000346454.7, ENST00000362072.8 ) - Associated Disease
- nicotine dependence
- Source Database
- DisGeNET
- Description
- Several SNPs (rs7131056, rs4274224, rs4648318, and rs6278) in DRD2, along with the Taq IA polymorphism (rs1800497) in ANKK1, revealed initial significant associations with ND in European Americans, but not after correction for multiple testing, indicating a weak association of DRD2 with ND.
- Pubmed
- 18354387
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00488595369744546
- Year of publication
- 2009
Drugs