Annotation Detail

Information
Associated Genes
WFS1
Associated Variants
FTO c.46-30685T>G ( ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1, ENST00000471389.6 )
FTO c.46-27777C>A ( ENST00000637001.1, ENST00000637969.1, ENST00000471389.6, ENST00000636218.1, ENST00000636491.1 )
rs4607103
WFS1 c.461-9A>G ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1, ENST00000684700.1 )
FTO c.46-30685T>G ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
FTO c.46-27777C>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
rs4607103
WFS1 c.461-9A>G ( ENST00000226760.5, ENST00000503569.5, ENST00000506362.2, ENST00000673991.1, ENST00000682275.1, ENST00000684087.1, ENST00000684700.1 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
While FTO rs8050136 and rs17817449, ADAMTS9 rs4607103, and WFS1 rs10010131 were initially associated with T2DM, this was lost upon multiple testing correction.
Pubmed
24145053
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.326514604929927
Year of publication
2013
Drugs