Annotation Detail

Information
Associated Genes
MEN1
Associated Variants
MEN1 MUTATION
MEN1 MUTATION
Associated Disease
Pituitary Diseases
Source Database
DisGeNET
Description
Germline mutations in MEN1 (encoding menin) result in multiple endocrine neoplasia type 1 and are found in very young patients with isolated sporadic pituitary adenomas, which highlights the importance of the chromosome 11q13 locus in pituitary tumorigenesis.
Pubmed
25350067
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0130292098598546
Drugs