Annotation Detail

Information
Associated Genes
TGFB1
Associated Variants
TGFB1 c.517-740G>T ( ENST00000221930.6, ENST00000600196.2, ENST00000677934.1 )
TGFB1 c.-1347T>C ( ENST00000539627.5, ENST00000604123.5 )
TGFB1 c.517-740G>T ( ENST00000221930.6, ENST00000600196.2, ENST00000677934.1 )
TGFB1 c.-1347T>C ( ENST00000539627.5, ENST00000604123.5 )
Associated Disease
Malignant tumor of colon
Source Database
DisGeNET
Description
Both TGFβ1 rs1800469 and rs4803455 were associated with colon cancer [odds ratio (OR) = 0.65 and 1.43, 95% CI = 0.51-0.84 and 1.18-1.73, respectively) but not rectal cancer.
Pubmed
21068203
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00244297684872273
Year of publication
2011
Drugs