Annotation Detail

Information
Associated Genes
INS
Associated Variants
PPARA p.Leu162Val (p.L162V) ( ENST00000402126.2, ENST00000407236.6 )
PPARA p.Leu162Val (p.L162V) ( ENST00000402126.2, ENST00000407236.6 )
Associated Disease
Diabetes
Source Database
DisGeNET
Description
In the placebo group, the G (162V) allele of rs1800206 increased the risk for diabetes by 1.9-fold (95% CI 1.05-3.58) and was associated with elevated levels of plasma glucose and insulin.
Pubmed
17317762
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.08
Year of publication
2007
Drugs