Annotation Detail

Information
Associated Genes
PPARA
Associated Variants
PPARA p.Leu162Val (p.L162V) ( ENST00000402126.2, ENST00000407236.6 )
PPARA p.Leu162Val (p.L162V) ( ENST00000402126.2, ENST00000407236.6 )
Associated Disease
diabetes mellitus
Source Database
DisGeNET
Description
The L162V polymorphism at the peroxisome proliferator activated receptor alpha locus modulates the risk of cardiovascular events associated with insulin resistance and diabetes mellitus: the Veterans Affairs HDL Intervention Trial (VA-HIT).
Pubmed
16221474
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0162304304980258
Year of publication
2006
Drugs