Annotation Detail
Information
- Associated Genes
- ATM
- Associated Variants
-
ATM p.Pro1054Arg (p.P1054R)
(
ENST00000278616.10,
ENST00000452508.7,
ENST00000531525.3,
ENST00000601453.3,
ENST00000675843.1,
ENST00000713844.1 )
ATM p.Pro1054Arg (p.P1054R) ( ENST00000278616.10, ENST00000452508.7, ENST00000531525.3, ENST00000601453.3, ENST00000675843.1, ENST00000713844.1 ) - Associated Disease
- Malignant neoplasm of prostate
- Source Database
- DisGeNET
- Description
- A missense variant in ATM, rs1800057, associated with increased prostate cancer risk, was found exclusively in two high toxicity patients but did not reach statistical significance for association with radiosensitivity (P = 0.488).
- Pubmed
- 19638463
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.010977227015051
- Year of publication
- 2009
Drugs