Annotation Detail

Information
Associated Genes
CYP11B2
Associated Variants
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
There was a trend towards a higher frequency of the T allele in subjects with a positive family history of hypertension (0.48 versus 0.42), but the C-344T genotype was not related to blood pressure under either diet Furthermore, when subjects were classified into salt-sensitive and salt-resistant groups, allelic distribution did not differ between the two groups (qT = 0.43 versus qT = 0.45).
Pubmed
10608469
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.143123487147592
Year of publication
1999
Drugs