Annotation Detail

Information
Associated Genes
ACE
Associated Variants
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C
Associated Disease
kidney failure
Source Database
DisGeNET
Description
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
Pubmed
12832734
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.025135811624945
Year of publication
2003
Drugs