Annotation Detail

Information
Associated Genes
CYP11B2
Associated Variants
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C
Associated Disease
Left ventricular dilatation
Source Database
DisGeNET
Description
Recently, the biallelic -344T/C polymorphism of the aldosterone synthase gene was associated with increased aldosterone levels, arterial hypertension, diastolic dysfunction, and left ventricular dilatation.
Pubmed
10720582
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2000
Drugs