Annotation Detail

Information
Associated Genes
AGTR1
Associated Variants
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C
Associated Disease
IgA glomerulonephritis
Source Database
DisGeNET
Description
The angiotensin I-converting enzyme (ACE) gene insertion/deletion (I/D), the angiotensinogen (AGT) gene, M235T, the aldosterone synthase (CYP11B2) gene, C-344T, and the angiotensin II type 1 receptor (AT1R) gene, A1166C, have been shown to be associated with IgA nephropathy (IgAN) and its progression.
Pubmed
21163122
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0241035829200061
Year of publication
2010
Drugs