Annotation Detail

Information
Associated Genes
AGT
Associated Variants
AGT MUTATION
AGT MUTATION
AGT p.Met259Thr (p.M259T) ( ENST00000679957.1, ENST00000681514.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000679684.1, ENST00000366667.6 )
CYP11B2 c.-344T>C
AGT p.Met259Thr (p.M259T) ( ENST00000366667.6, ENST00000679684.1, ENST00000679957.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000681514.1 )
CYP11B2 c.-344T>C
Associated Disease
Chronic glomerulonephritis
Source Database
DisGeNET
Description
We evaluate whether angiotensinogen AGT M235T (rs699), angiotensin-converting enzyme ACE (I/D) (rs4646994) and aldosterone synthase CYP11B2 -344C/T (rs1799998) polymorphisms can be genetic risk factors of chronic glomerulonephritis (GN) in the Polish population.
Pubmed
23681285
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00263847385068233
Year of publication
2015
Drugs