Annotation Detail
Information
- Associated Genes
- ACE
- Associated Variants
-
ADD1 p.Gly460Trp (p.G460W)
(
ENST00000264758.11,
ENST00000398129.5,
ENST00000683351.1 )
CYP11B2 c.-344T>C
ADD1 p.Gly460Trp (p.G460W) ( ENST00000264758.11, ENST00000398129.5, ENST00000683351.1 )
CYP11B2 c.-344T>C - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- In a prospective analysis of a Caucasian population, we recently found that the genes encoding angiotensin-converting enzyme (ACE, I/D polymorphism), alpha-adducin (Gly460Trp) and aldosterone synthase (-344C/T) jointly influence the incidence of hypertension.
- Pubmed
- 15097233
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.44
- Year of publication
- 2004
Drugs