Annotation Detail
Information
- Associated Genes
- CYP11B2
- Associated Variants
-
ADD1 p.Gly460Trp (p.G460W)
(
ENST00000264758.11,
ENST00000398129.5,
ENST00000683351.1 )
CYP11B2 c.-344T>C
ADD1 p.Gly460Trp (p.G460W) ( ENST00000264758.11, ENST00000398129.5, ENST00000683351.1 )
CYP11B2 c.-344T>C - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- The ACE I/D, alpha-adducin Gly460Trp and aldosterone synthase -344C/T polymorphisms interact to influence systolic blood pressure in Chinese, suggesting that these genes might indeed predispose to hypertension, especially in an ecogenetic context characterized by a high salt intake.
- Pubmed
- 15097233
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.143123487147592
- Year of publication
- 2004
Drugs