Annotation Detail

Information
Associated Genes
CYP11B2
Associated Variants
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
Previous studies have shown that the aldosterone synthase promoter polymorphism -344T/C influences aldosterone levels and is associated with hypertension, a risk factor for the initiation and progression of diabetic nephropathy.
Pubmed
16759311
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.143123487147592
Year of publication
2006
Drugs