Annotation Detail

Information
Associated Genes
CYP11B2
Associated Variants
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
The C-344T polymorphism in the 5'-flanking region of the aldosterone synthase (CYP11B2) gene has been suggested to be associated with hypertension and disturbed circadian blood pressure (BP) rhythm through its effect on aldosterone synthesis.
Pubmed
11725161
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.143123487147592
Year of publication
2001
Drugs