Annotation Detail
Information
- Associated Genes
- AGXT
- Associated Variants
-
AGT p.Met259Thr (p.M259T)
(
ENST00000679957.1,
ENST00000681514.1,
ENST00000680041.1,
ENST00000680783.1,
ENST00000681269.1,
ENST00000679684.1,
ENST00000366667.6 )
CYP11B2 c.-344T>C
AGT p.Met259Thr (p.M259T) ( ENST00000366667.6, ENST00000679684.1, ENST00000679957.1, ENST00000680041.1, ENST00000680783.1, ENST00000681269.1, ENST00000681514.1 )
CYP11B2 c.-344T>C - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- Hypertension association reached genome-wide significance for the two variants, specifically, P=7.3 × 10(-10) for AGT rs699 and P=3.9 × 10(-8) for CYP11B2 rs1799998.
- Pubmed
- 22456346
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0114005586273727
- Year of publication
- 2012
Drugs