Annotation Detail
Information
- Associated Genes
- CYP11B2
- Associated Variants
-
CYP11B2 c.-344T>C
CYP11B2 c.-344T>C - Associated Disease
- IgA glomerulonephritis
- Source Database
- DisGeNET
- Description
- The angiotensin I-converting enzyme (ACE) gene insertion/deletion (I/D), the angiotensinogen (AGT) gene, M235T, the aldosterone synthase (CYP11B2) gene, C-344T, and the angiotensin II type 1 receptor (AT1R) gene, A1166C, have been shown to be associated with IgA nephropathy (IgAN) and its progression.
- Pubmed
- 21163122
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00590570783731011
- Year of publication
- 2010
Drugs