Annotation Detail
Information
- Associated Genes
- TH
- Associated Variants
-
TH MUTATION
TH MUTATION - Associated Disease
- Parkinson disease
- Source Database
- DisGeNET
- Description
- Loss of the Grx1 homolog also exacerbated the neurodegenerative phenotype in other C. elegans models, including overexpression of human α-synuclein and overexpression of tyrosine hydroxylase (a model of sporadic PD).
- Pubmed
- 25355420
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN,RGD
- DisGENET score for the Gene Disease association
- 0.0965454796318243
Drugs