Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Met129Val (p.M129V) ( ENST00000379440.9, ENST00000430350.2, ENST00000457586.2, ENST00000424424.2 )
PRNP p.Met129Val (p.M129V) ( ENST00000430350.2, ENST00000457586.2, ENST00000424424.2, ENST00000379440.9 )
Associated Disease
Prion Diseases
Source Database
DisGeNET
Description
The genetic variant at codon 129 (M129V) of the prion protein gene (PRNP) is considered to be a major genetic risk factor for prion diseases.
Pubmed
20592456
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.481088376032419
Year of publication
2010
Drugs