Annotation Detail

Information
Associated Genes
PRNP
Associated Variants
PRNP p.Met129Val (p.M129V) ( ENST00000379440.9, ENST00000430350.2, ENST00000457586.2, ENST00000424424.2 )
PRNP p.Met129Val (p.M129V) ( ENST00000430350.2, ENST00000457586.2, ENST00000424424.2, ENST00000379440.9 )
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
The association between the methionine/valine (M/V) polymorphism (rs1799990) in the PRNP gene and the risk of Alzheimer disease: an update by meta-analysis.
DisGENET score for the Gene Disease association
0.177294231272165
Year of publication
2013
Pubmed
23399523
Original source reporting the Gene Disease association
BeFree
Drugs