Annotation Detail

Information
Associated Genes
SLC6A3
Associated Variants
SLC6A3 MUTATION
SLC6A3 MUTATION
Associated Disease
Parkinson disease
Source Database
DisGeNET
Description
Here we show that SNCA transcripts in circulating blood cells are paradoxically reduced in early stage, untreated and dopamine transporter neuroimaging-supported Parkinson's disease in three independent regional, national, and international populations representing 500 cases and 363 controls and on three analogue and digital platforms with P < 0.0001 in meta-analysis.
Pubmed
26220939
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.162940149660312
Drugs