Annotation Detail

Information
Associated Genes
MMP1
Associated Variants
MMP1 MUTATION
MMP1 MUTATION
Associated Disease
Pain
Source Database
DisGeNET
Description
Our results suggest that 2ccPA significantly reduces the pain response to OA by inducing hyaluronic acid production and suppressing MMP-1, -3, and -13 production in synoviocytes and chondrocytes.
Pubmed
25123228
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs