Annotation Detail
Information
- Associated Genes
- ATR
- Associated Variants
-
ATR MUTATION
ATR MUTATION - Associated Disease
- osteosarcoma
- Source Database
- DisGeNET
- Description
- Together, these findings implicate Aven in ATR-Chk1 signalling and point towards Chk1 inhibition as a strategy to sensitize human osteosarcomas to chemotherapy.
- Pubmed
- 25757065
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs