Annotation Detail

Information
Associated Genes
ICAM1
Associated Variants
ICAM1 p.Lys56Arg (p.K56R) ( ENST00000264832.8, ENST00000423829.2 )
ICAM1 p.Lys56Met (p.K56M) ( ENST00000264832.8, ENST00000423829.2 )
ICAM1 p.Gly241Arg (p.G241R) ( ENST00000264832.8, ENST00000423829.2 )
ICAM1 p.Lys56Arg (p.K56R) ( ENST00000264832.8, ENST00000423829.2 )
ICAM1 p.Lys56Met (p.K56M) ( ENST00000264832.8, ENST00000423829.2 )
ICAM1 p.Gly241Arg (p.G241R) ( ENST00000264832.8, ENST00000423829.2 )
Associated Disease
Cardiovascular Diseases
Source Database
DisGeNET
Description
The objective of this study was to examine the association of 2 nonsynonymous intercellular adhesion molecule 1 (ICAM1) gene variants (Lys56Met and Gly241Arg) with baseline plasma soluble ICAM1 concentrations and with risk of total and selected cardiovascular disease (CVD) events in a prospective cohort of 23 014 apparently healthy white American women followed for 10 years.
Pubmed
17962597
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.135992664366
Year of publication
2007
Drugs