Annotation Detail

Information
Associated Genes
TNF
Associated Variants
IL19 c.-149+2211A>G ( ENST00000664374.2, ENST00000659065.2, ENST00000659642.2, ENST00000659997.3, ENST00000656872.2 )
rs1799964
IL19 c.-149+2211A>G ( ENST00000659065.2, ENST00000659642.2, ENST00000664374.2, ENST00000656872.2, ENST00000659997.3 )
rs1799964
Associated Disease
Malignant neoplasm of lung
Source Database
DisGeNET
Description
Bayesian correction for multiple comparisons suggests that chance is unlikely to explain our findings (although epigenetic mechanisms may be in effect), which support our hypotheses, suggesting that IL10 rs1800871 is a susceptibility marker for oropharyngeal and lung cancers, and that TNF rs1799964 is associated with smoking-related cancers among never smokers.
Pubmed
20112337
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0423674713511587
Year of publication
2010
Drugs