Annotation Detail
Information
- Associated Genes
- IL6R
- Associated Variants
-
IL6R MUTATION
IL6R MUTATION - Associated Disease
- Degenerative polyarthritis
- Source Database
- DisGeNET
- Description
- Secreted Frizzled-related protein 3 (sFRP3)-mediated suppression of interleukin-6 receptor release by A disintegrin and metalloprotease 17 (ADAM17) is abrogated in the osteoarthritis-associated rare double variant of sFRP3.
- Pubmed
- 25846075
- Section of the abstract supporting the evidence
- TITLE
- Number of the section of the abstract supporting the evidence
- 0
- Number of the sentence supporting the evidence
- 0
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs