Annotation Detail
Information
- Associated Genes
- EPHB2
- Associated Variants
-
EPHB2 MUTATION
EPHB2 MUTATION - Associated Disease
- Opioid withdrawal
- Source Database
- DisGeNET
- Description
- Our data suggest that H2S prevents the development of opioid withdrawal-induced hyperalgesia via suppression of synthesis of CGRP in spine through inhibition of AC/cAMP and PKC/Raf-1/ERK pathways.
- Pubmed
- 24824948
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs