Annotation Detail

Information
Associated Genes
RET
Associated Variants
RET p.Gly691Ser (p.G691S) ( ENST00000713926.1, ENST00000355710.8, ENST00000340058.6, ENST00000615310.5 )
RET p.Gly691Ser (p.G691S) ( ENST00000615310.5, ENST00000340058.6, ENST00000355710.8, ENST00000713926.1 )
Associated Disease
multiple endocrine neoplasia type 2A
Source Database
DisGeNET
Description
In 46 cases of sporadic MTCs, we also studied the cosegregation of somatic RET gene mutation and G691S polymorphism as well as the linkage of the polymorphism with RET germline mutation in 60 members of eight multiple endocrine neoplasia type 2 families.
Pubmed
15240649
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.613995490717024
Year of publication
2004
Drugs