Annotation Detail

Information
Associated Genes
SERPINE1
Associated Variants
rs2227631
MMP3 SNV
rs2227631
MMP3 SNV
Associated Disease
Alzheimer's disease
Source Database
DisGeNET
Description
The purpose of this study was to explore the association between the SERPINE1 promoter polymorphisms (rs1799889 and rs2227631) and the risk of depression in AD and to determine the relationship between these 2 polymorphisms and the response to paroxetine treatment in AD patients with depressive symptoms.
Pubmed
22503724
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00581983144552528
Year of publication
2012
Drugs