Annotation Detail
Information
- Associated Genes
- MC4R
- Associated Variants
-
MC4R MUTATION
MC4R MUTATION - Associated Disease
- Obesity, Morbid
- Source Database
- DisGeNET
- Description
- Melanocortin 4 receptor (MC4R) is a key factor in regulating energy homeostasis, and null mutations occurring in the gene encoding MC4R cause severe early-onset morbid obesity in humans.
- Pubmed
- 24780838
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 1
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0189685934372187
Drugs