Annotation Detail

Information
Associated Genes
HLA-DRB1
Associated Variants
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
Associated Disease
multiple sclerosis
Source Database
DisGeNET
Description
The +190 G/A (rs1799864) polymorphism in the C-C chemokine receptor 2 (CCR2) gene is associated with susceptibility to multiple sclerosis in HLA-DRB1*15:01-negative individuals.
Pubmed
25604634
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.296822005372207
Year of publication
2015
Drugs