Annotation Detail

Information
Associated Genes
TNF
Associated Variants
TGFB1 c.-1347T>C ( ENST00000539627.5, ENST00000604123.5 )
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
TGFB1 SNV
TGFB1 c.-1347T>C ( ENST00000539627.5, ENST00000604123.5 )
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
TGFB1 SNV
Associated Disease
Migraine Disorders
Source Database
DisGeNET
Description
Regarding any history of migraine, the multivariable-adjusted odds ratios (95% confidence intervals) for TNF rs673 were 0.52 (0.30 to 0.89), for TGFB1 rs1800469 0.93 (0.89 to 0.98), and for CCR2 rs1799864 1.12 (1.03 to 1.21).
Pubmed
19559392
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.138902580088762
Year of publication
2009
Drugs