Annotation Detail
Information
- Associated Genes
- VDR
- Associated Variants
-
VDR MUTATION
VDR MUTATION - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Two cohorts were studied: 1) 118 subjects classified according to their BMI (lean, overweight, obese, or morbidly obese [MO]) and their glycemic status (normoglycemic [NG] and prediabetic and diabetic [P&D]); and 2) 30 obese subjects (BMI > 30 kg/m(2)) classified as NG and P&D. VDR gene expression was analyzed during preadipocyte differentiation and in vitro stimulation with 1,25(OH)2D3 of AT explants from donors with different BMI values.
- Pubmed
- 25706239
- Section of the abstract supporting the evidence
- DESIGN AND PATIENTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.0113682210189702
Drugs