Annotation Detail

Information
Associated Genes
CCR2
Associated Variants
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
CCR2 p.Val64Ile (p.V64I) ( ENST00000400888.2, ENST00000445132.3 )
Associated Disease
Carotid Atherosclerosis
Source Database
DisGeNET
Description
Subjects who had both the MCP-1 CC genotype and were heterozygotic or homozygotic for the CCR2 V64I genotype (rs1799864; n = 12) had an even higher risk of carotid atherosclerosis (odds ratio 6.14, 95% confidence interval 1.82-20.73; p = 0.0037).
Pubmed
19506371
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2009
Drugs