Annotation Detail
Information
- Associated Genes
- NOS3
- Associated Variants
-
NOS3 MUTATION
NOS3 MUTATION - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- Given that arginase-II (Arg-II) exerts some of its biological functions through crosstalk with signal transduction pathways, and that p38 mitogen-activated protein kinase (p38mapk) is involved in eNOS-uncoupling, we investigated here whether p38mapk is involved in Arg-II-mediated eNOS-uncoupling in a high fat diet (HFD)-induced obesity mouse model.
- Pubmed
- 25034973
- Section of the abstract supporting the evidence
- BACKGROUND
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 3
- Original source reporting the Gene Disease association
- BeFree,GAD,RGD
- DisGENET score for the Gene Disease association
- 0.0964496717183753
Drugs