Annotation Detail
Information
- Associated Genes
- GNPDA2
- Associated Variants
-
GNPDA2 MUTATION
GNPDA2 MUTATION - Associated Disease
- obesity
- Source Database
- DisGeNET
- Description
- When body mass index and waist circumference were further adjusted, the association of MC4R with type 2 diabetes remained significant (P = 1.81×10(-2)) and that of GNPDA2 was attenuated (P = 1.26×10(-1)), suggesting the effect of the locus including GNPDA2 on type 2 diabetes may be mediated through obesity.
- Pubmed
- 25093408
- Section of the abstract supporting the evidence
- RESULTS
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 7
- Original source reporting the Gene Disease association
- BeFree,CTD_human,GAD
- DisGENET score for the Gene Disease association
- 0.152942950698469
Drugs