Annotation Detail

Information
Associated Genes
ERCC2
Associated Variants
ERCC2 p.Asp312Asn (p.D312N) ( ENST00000391944.8, ENST00000391945.10, ENST00000485403.6, ENST00000684407.1 )
RAD23B p.Ala249Val (p.A249V) ( ENST00000358015.8, ENST00000416373.6 )
ERCC2 p.Asp312Asn (p.D312N) ( ENST00000391944.8, ENST00000391945.10, ENST00000485403.6, ENST00000684407.1 )
RAD23B p.Ala249Val (p.A249V) ( ENST00000358015.8, ENST00000416373.6 )
Associated Disease
Malignant neoplasm of urinary bladder
Source Database
DisGeNET
Description
In multifactor dimensionality reduction (MDR) analysis, the five-factor model including smoking, CCNH V270A, ERCC6 M1097V, RAD23B A249V and XPD D312N had the best ability to predict bladder cancer risk.
Pubmed
17728339
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0835408927354731
Year of publication
2007
Drugs