Annotation Detail
Information
- Associated Genes
- CSRP1
- Associated Variants
-
CSRP1 MUTATION
CSRP1 MUTATION - Associated Disease
- Neurofibromatosis 2
- Source Database
- DisGeNET
- Description
- In the present study, we investigated various components of the NF2-Hippo pathway, and eventually found that MM cells frequently showed downregulation of LIM-domain protein AJUBA, a binding partner of large tumor suppressor type 2 (LATS2), which is one of the last-step kinases of the NF2-Hippo pathway.
- Pubmed
- 24336325
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs