Annotation Detail
Information
- Associated Genes
- TIMP3
- Associated Variants
-
rs1799750
rs1799750
rs2276109
MMP2 c.-1586C>T ( ENST00000570308.5 )
rs3918242
SYN3 c.711+64209A>G ( ENST00000358763.7 )
SYN1 c.775-9619A>C ( ENST00000295987.13, ENST00000340666.5 )
rs2276109
MMP2 c.-1586C>T ( ENST00000570308.5 )
rs3918242
SYN3 c.711+64208A>G ( ENST00000358763.7 )
SYN1 c.775-9619A>C ( ENST00000295987.13, ENST00000340666.5 ) - Associated Disease
- Malignant neoplasm of urinary bladder
- Source Database
- DisGeNET
- Description
- To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (BC).
- Pubmed
- 23819551
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2014
Drugs